Using a special action, Cleanance Comedomed, a breakthrough from Laboratoires Eau Thermale Avène, addresses visible and invisible imperfections and reduces their recurrence. Its efficacy has been demonstrated for seven days. Comedoclastin, a plant extract from milk thistle seeds, is included in the formulation of Cleanance Comedomed, an expert skincare product for oily, acne-prone skin. This proprietary chemical effectively targets blackheads, minimizes pre-existing blemishes, and inhibits the formation of new ones. Cleanance Comedomed has clinically proven anti-reapearance activity and, when used twice daily, minimizes blemishes within seven days. Teens and adults above the age of twelve can utilize it. The skin is left mattified by its fast-absorbing, non-greasy texture, which is non-comedogenic and has a high tolerance for skin prone to blemishes. Cleanance Comedomed (except from oral isotretinoin) can be used on its own, in combination with other products, or following acne therapy.